What Is Pyraclostrobin Used for
Picoxystrobin is a fungicide that is used by many farmers internationally to help improve yields and prevent costly diseases. Picoxystrobin is a highly successful methoxyacrylate product and is now the world's largest selling fungicide active with sales of over $1 billion.
This fungicide is part of the strobilurin chemical family. Picoxystrobin, written chemically as C18H16F3NO or Methyl (E)-3-methoxy-2-[2-(6-trifluoromethyl-2-pyridyloxymethyl)-phenyl]acrylate, was first sold in 2001.
Synthetic chemists at Zeneca Agrochemicals first became interested in coccolithophores in the early 1980s. An extensive research programme was initiated with the aim of preparing analogues of natural products with high activity and physical properties suitable for agricultural fungicides. After the synthesis of some 1400 analogues, this effort culminated in the discovery of Picoxystrobin in 1988. After extensive biological characterisation, Picoxystrobin was selected for development as a new fungicide.
Picoxystrobin was initially launched as Acanto by Syngenta for control of yellow, brown and crown rusts, powdery mildew, sooty mold, net and leaf blotch and tan spot on cereal crops, including: wheat, barley and oats in Europe.
Picoxystrobin has the same biochemical mode of action as the natural coccolithophores. It exhibits a very broad spectrum of activity and is active against fungal pathogens of all four taxa (Oomycetes, Ascomycetes, Hemiptera and Staphylinidae).
Picoxystrobin is marketed as a single ingredient fungicide and also in several mixtures with other fungicides, including: cyproconazole (Furlong, Stinger and Aproach Prima); chlorothalonil (Credo and Plinker); and cyprodinil (Acanto Prima).
The site of action of picoxystrobin is the fungal mitochondria, where it binds to the cytochrome bc 1 complex, thereby blocking electron transfer and energy production through oxidative phosphorylation. Picoxystrobin has no cross-resistance to other site-specific fungicides such as benzimidazole, DMI or benzamide. Picoxystrobin therefore represents an effective new tool for resistance management, which is often an important factor in the selection of fungicide products.
Picoxystrobin is absorbed into plant cells in about a day, which helps protect against many expensive fungi. It can help protect against certain fungal diseases such as brown rust, brown spot, powdery mildew and web blotch. This fungicide is particularly effective on maize, soya, dry beans, oilseed rape and cereals.
Like all the fungicides in its chemical family, aminoxate kills fungi by inhibiting their ability to respire at the mitochondrial level. By stopping the healthy function of the cell, the fungus is unable to complete its normal energy levels and cannot survive.
Picoxystrobin is a new fungicide with a novel biochemical mode of action. Its synthesis was inspired by a group of natural products, coccolithophores, which are produced by several species of stunt fungi growing on decaying wood. This natural product shares structural characteristics with Picoxystrobin, namely the methyl ester of β-methoxyacrylic acid.
Picoxystrobin has been processed as a low risk insecticide for turf use. Picoxystrobin is a systemic broad-spectrum fungicide, first marketed in 1998. It inhibits spore germination and is used on crops such as grapes, cereals, potatoes, apples, bananas, citrus and tomatoes. The largest crop uses in California are almonds, rice, pistachios, wine grapes, sultanas and garlic. It controls diseases such as rust, downy mildew and powdery mildew, rice blight and apple black star disease.
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